If you wants to run multiple websites using the same Laravel installation while keeping tenant specific data separated for fully independent multi-domain setups then it is pretty easily possible with this multi-tenant laravel package.
Here is the github link for the package: https://github.com/tenancy/multi-tenant
With this package, you can serve multiple websites each with one or more hostnames from the same codebase. It has clear separation of database, assets & also provides ability to override logic per tenant.
This is suitable for marketing companies or startups which are building Software as a Service(SaaS).
I know this architecture is opposite to famous micro-service architecture, but just posting it in case someone is in the need to do so.